
SYMPTOMS OF INSONMIA
Insomnia is described as the disturbance
of sleep, either by delay in falling asleep, failure to maintain sleep,
early waking, or in some extreme cases total absence of sleep.
Why does it happen
Insomnia is a common complaint, and can
occur with almost anybody. Onset of insomnia can be triggered by
depression, pain, chronic illness, stress or a disturbance in sleeping
routine.
Treatments
Herbal remedies
Herbal remedies can sometimes help, such as Nytol herbal, or Badger's
sleep balm.
OTC Medication
OTC medication available include Sominex
and Nytol. OTC sleeping aids should be for short term use only as
dependance can occur. OTC treatment for insomnia usually contains
sedating antihistamines, therefore any other antihistamines should not
be taken at the same time e.g for allergy chlorpheniramine, loratidine
etc.
Prescription medications
Benzodiazepines
Benzodiaepines cause drowsiness and aid sleep. They also have the added
benifit of reducing aggression and anxiety. They also reduce muscle tone
and act as a muscle relaxant, which can help if the insomnia is caused
by pain due to tight muscle spasms. Benzodiazepines act on GABA
receptors in the brain. One common side-effect is a hangover effect the
next morning, due to long duration of action of some benzodiazepines.
Z-drugs: zopiclone, zolpidem
The Z-drugs are a new class of hypnotics which are
non-benzodiazepines. They are design to reduce sideeffects caused by
benzodiazepines. Common sideeffects include metallic taste, and
hangover effects.
Barbiturates
Barbiturates are not commonly used as hypnotics anymore due to the high
chance of drug interactions (due to induction of hepatic cytochrome P450
enzymes), high risk of tolerance and dependence, and they are highly
toxic on overdose.
OTHER USEFUL INFORMATION FOR THE EXAM
Short-acting benzodiazepines
temazepam, loprazolam, and lormetazepam
Long acting benzodiazepines
Flurazepam, flunitrazepam, nitrazepam. |
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