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Pre-Registration Exam Practice
Questions
BNF Exercise Section 1
Central Nervous
System – Part 1
Closed Book
1)
Which of the following is NOT a side effect of
benzodiazepines:
A.
Decrease in responsiveness
B.
Antisocial behaviour
C.
Aggression
D.
Excitement
E.
Convulsions
2) Use of chlormethiazole in alcohol withdrawal should NOT
be longer than
A.
5 days
B.
6 days
C.
7 days
D.
8 days
E.
9 days
3) Which of the following is not an example of
extra-pyramidal side effects:
A.
Tardive Dyskinesia
B.
Locomotor Ataxia
C.
Parkinsonian tremor
D.
Dystonia
E.
Akathisia
4.
Which of the following anti-psychotic can be used to
treat violent patients without causing stupor? Agitated
states in the elderly can also be control with the drug in
the dose of 10 mg to 25mg with little risk of inducing
confusion.
A.
Loxapine
B.
Promazine
C.
Thioridazine
D.
Chlorpromazine
E.
Sulpiride
5.
Which of the following is not a possible side effect
of clozapine?
A.
Prostatic hypertrophy
B.
Constipation
C.
Agranulocytosis
D.
Arrhythmias
E.
Temperature deregulation
6.
Lithium dose is adjusted according to which of the
following plasma concentration
A.
0.3 to 0.6mmol/l
B.
0.4 to 1.3mmol/l
C.
0.4 to 1mmol/l
D.
0.5 to 1.3mmol/l
E.
0.6 to 1.4mmol/l
Directions Summarised
|
|
A
1,2,3 |
B
1,2 only |
C
2,3 only |
D
1 only |
E
3 only |
7) Use of diazepam is contra-indicated or cautioned in which
of the following conditions:
1.
Myasthenia gravis
2.
Acute respiratory distress
3.
Liver cirrhosis
8) Abrupt withdrawal of benzodiazepines can cause which of
following:
1.
Psychosis
2.
Delirium
3.
Confusion
9) Which of the following statements regarding
benzodiazepines is incorrect
1.
Withdrawal symptoms can occur anytime up to 3 weeks
after stopping a long acting benzodiazepine
2.
Withdrawal syndrome can occur within one or 2 hours
after stopping a short acting benzodiazepine
3.
Rebound drowsiness can be one of the symptoms of
withdrawal
10) Which of the following statements regarding
clomethiazole is correct:
1.
It has a long duration of action
2.
Use in alcohol withdrawal is undesirable
3.
It is a useful hypnotic in the elderly as it has
little hangover effects
Directions Summarised
|
|
A
1,2,3 |
B
1,2 only |
C
2,3 only |
D
1 only |
E
3 only |
11) Use of antipsychotics is contra-indicated in which of
the following:
1.
Comatose state
2.
CNS depression
3.
Phaeochromocytoma (Vascular tumour of adrenal
medulla)
12) Which of the following is a licensed indication of
lithium
1.
Treatment of newly diagnosed depression
2.
Treatment of bipolar disorder
3.
Prophylaxis of bipolar disorder
13) Long term use of lithium is associated with
1.
Memory loss
2.
Cognitive impairment
3.
Thyroid dysfunction
Directions Summarised
|
|
|
First
Statement |
Second Statement |
|
|
A |
True |
True |
2nd statement is a correct explanation of
the first statement |
|
B |
True |
True |
2nd statement is NOT a correct
explanation of the first |
C
|
True |
False |
|
|
D |
False |
True |
|
E |
False |
False |
14)
Statement one:
Use of anxiolytics should be avoided during bereavement
Statement two:
Psychological adjustment during bereavement may be inhibited
by the use of anxiolytics
Directions Summarised |
|
|
First
Statement |
Second Statement |
|
|
A |
True |
True |
2nd statement is a correct explanation of
the first statement |
|
B |
True |
True |
2nd statement is NOT a correct
explanation of the first |
C
|
True |
False |
|
|
D |
False |
True |
|
E |
False |
False |
15)
Statement one:
Lorazepam and oxazepam are preferred benzodiazepines in
hepatic impairment
Statement two:
Lorazepam and oxazepam carry a lower risk of withdrawal
symptoms
16)
Statement one:
Beta-blockers have an effect on psychological symptoms, such
as worry, tension and fear
Statement two:
Beta-blockers can reduce autonomic symptoms such as
palpitations and tremor. |
